Oct 4, 2016 · "Uraemia" is a term that tends to be applied to describe the syndrome associated with an accumulation of all sorts of renally cleared waste products, and is not necessarily referring to the accumulation of urea alone. However, urea is the most abundant waster product among those which accumulate, and it seems to have some important …
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In uremia, PTH and phosphorus overload are both independently associated with major changes related to the cardiac remodeling process, emphasizing the need for a better control of these factors in chronic kidney disease. Parathyroid hormone and phosphorus overload in uremia: impact on cardiovascular system ...
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Mar 29, 2024 · Uremia is a clinical condition associated with declining renal function and is characterized by fluid overload, electrolyte imbalances, metabolic abnormalities, and physiological changes. The term "uremia" literally means "urine in the blood," which develops most commonly in chronic and end-stage re …
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Dec 23, 2016 · Uremia refers to the pathological manifestations that occur with severe azotemia or kidney failure. Symptoms of uremia develop as kidney function declines and waste products accumulate in the blood. Chronic kidney disease is defined as kidney damage or decreased kidney function lasting at least 3 months. It is staged based on …
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Oct 24, 2012 · 1. Magnitude of the Problem: Mortality in Uremia. The development of CKD is associated with a significant increase in all-cause mortality [].As compared to the general population, a 2-fold incidence of mortality of CKD patients over 65 years and a 36-fold increase in mortality of CKD patients aged 16 to 49 years has been reported [].The main …
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Nov 1, 2016 · Beginning at postoperative week 4, the uremia rats were treated with daily 150 mg/kg berberine by oral gavage for 6 weeks. To assess the intestinal mucosal barrier changes, blood samples were collected for measuring the serum D-lactate level, and terminal ileum tissue samples were used for analyses of intestinal permeability, …
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The study revealed, for the first time, that uremia results in depletion of the key protein constituents of the colonic tight junction, a phenomenon which can account for the impaired intestinal barrier function and contribute to the systemic inflammation in CKD.
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During acute or chronic uremia, the cumulative harmful effects of uremic toxins result in numerous health problems and, ultimately, mortality. Previous research has identified that uremic retention solutes originate from the gut microbiome, indicating that uremia may be closely associated with gut m …
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Protein carbamylation links inflammation, smoking, uremia and atherogenesis Nat Med. 2007 Oct;13(10):1176-84. doi: 10.1038/nm1637. Epub 2007 Sep 9. Authors Zeneng Wang 1 , Stephen J Nicholls, E Rene Rodriguez, Outi Kummu, Sohvi Hörkk ö, John Barnard, Wanda F Reynolds, Eric J ...
Abnormal bone turnover and mineral metabolism is observed in patients on dialysis. Secondary hyperparathyroidism (SHP) develops in response to mineral metabolism changes accompanying renal failure. As a factor of disease progression, the phenomenon of skeletal resistance to parathyroid hormone (PTH) …
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